期刊
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
卷 34, 期 1, 页码 201-205出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/07391102.2015.1010584
关键词
DNA; binding parameters; degree of denaturation; DNA-ligand complexes; helix-coil transition
The melting transition of DNA-ligand complexes, allowing for two binding mechanisms to different DNA conformations is treated theoretically. The obtained results express the behavior of the experimentally measurable quantities, degree of denaturation, and concentrations of bound ligands on the temperature. The range of binding parameters is obtained, where denaturation curves become multiphasic. The possible application to the nanocomposites crystallization is discussed.
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