Regioselectively modified polysaccharide derivatives as chiral stationary phases in high-performance liquid chromatography

This review summarizes several regioselectively modified polysaccharide derivatives which have been prepared in order to be used for chiral separations chromatography. The goal was to combine the effects of the known tris-arylcarbamate and tris-arylesters of polysaccharides. The use of new materials as chiral stationary phases (CSPs) in liquid chromatography for enantiomeric discrimination was investigated and compared to the homogeneously substituted polysaccharide derivatives. The different works describing the preparations, the performances and the applications of regioselectively modified polysaccharide derivatives have been resumed. (C) 2001 Elsevier Science B.V; All rights reserved.