SigE is a chaperone for the Salmonella enterica serovar typhimurium invasion protein SigD

SigD is translocated into eucaryotic cells by a type III secretion system. In this work, evidence that the putative chaperone SigE directly interacts with SigD is presented. A bacterial two-hybrid system demonstrated that SigE can interact with itself and SigD. In addition, SigD was specifically copurified,vith SigE His, on a nickel column.