期刊
BRAIN AND COGNITION
卷 45, 期 1, 页码 64-78出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1006/brcg.2000.1256
关键词
posttraumatic stress disorder; frontal brain systems; neuropsychology; comparative neuropsychology
资金
- NIAAA NIH HHS [R37-AA07112] Funding Source: Medline
- NIMH NIH HHS [F31 MH011954, F31 MH011954-01] Funding Source: Medline
- PHS HHS [K05-00219] Funding Source: Medline
Clinical observations have suggested that individuals who have suffered traumatic stressful events exhibit disruption in abilities mediated by frontal brain systems. Therefore, this study employed tasks sensitive to frontal lobe dysfunction, including delayed response (DR), delayed alternation (DA), object alternation (OA), delayed matching-to-sample (DMTS), and delayed nonmatching-to-sample (DNMTS), with participants having posttraumatic stress disorder (PTSD). Compared to controls, the PTSD participants were unimpaired on DA and DMTS, but they showed deficits on DR, OA, and DNMTS tasks. This pattern of results suggests disruption of functioning in selective prefrontal brain systems. Results are discussed in the context of the neuropsychological features of PTSD, as well as possible neuropathological and etiological underpinnings of this disorder. (C) 2001 Academic Press.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据