期刊
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
卷 1833, 期 11, 页码 2473-2478出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbamcr.2013.01.027
关键词
Cargo receptor; COPII coated vesicles; Endoplasmic reticulum exit site; Glycosylphosphatidylinositol; Wnt
资金
- Japan Society for the Promotion of Science
- Grants-in-Aid for Scientific Research [21247018, 23687017] Funding Source: KAKEN
In this review on the transport of glycosylphosphatidylinositol-anchored proteins (GPI-APs), we focus on events that occur in the endoplasmic reticulum after the transfer of GPI to proteins. These events include structural remodeling of both the lipid and glycan moieties of GPI, recruitment of GPI-APs into ER exit sites, association with the cargo receptor, p24 protein complex, and packaging into COPII coated transport vesicles. Similarities with the transport of Wnt proteins are also discussed. This article is part of a Special Issue entitled: Functional and structural diversity of endoplasmic reticulum. (C) 2013 Elsevier B.V. All rights reserved.
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