期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 2, 期 2, 页码 138-145出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/35052082
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Filamins are large actin-binding proteins that stabilize delicate three-dimensional actin webs and link them to cellular membranes. They integrate cellular architectural and signalling functions and are essential for fetal development and cell locomotion. Here, we describe the history, structure and function of this group of proteins.
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