期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 12, 期 1, 页码 41-47出版社
ELSEVIER SCI LTD
DOI: 10.1016/S0958-1669(00)00175-0
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Microarrays have emerged as indispensable research tools for gene expression profiling and mutation analysis. New classification of cancer subtypes, dissecting the yeast metabolism and large-scale genotyping of human single nucleotide polymorphisms are important results being obtained with this technique. Realizing the microsphere-based massively parallel signature sequencing technique as fluid microarrays, building new types of protein arrays and constructing miniaturized flow-through systems, which can potentially take this technology from the research bench into industrial, clinical and other routine applications, exemplify the intense developments that are now ongoing in this field.
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