期刊
AMERICAN JOURNAL OF HUMAN GENETICS
卷 68, 期 2, 页码 533-536出版社
CELL PRESS
DOI: 10.1086/318190
关键词
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We measured the proportion of mutant mtDNA (mutation load) in 82 primary oocytes from a woman who harbored the A3243G mtDNA mutation. The frequency distribution of mutation load indicates that random drift is the principal mechanism that determines the level of mutant mtDNA within individual oocytes.
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