期刊
NEUROREPORT
卷 12, 期 2, 页码 379-383出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200102120-00039
关键词
cerebral cortex; facial expressions; functional magnetic resonance imaging; human; limbic system
资金
- NIMH NIH HHS [MH-60219] Funding Source: Medline
Repeated presentations of emotional facial expressions were used to assess habituation in the human brain using fMRI. Significant fMRI signal decrement was present in the left dorsolateral prefrontal and premotor cortex, and right amygdala. Within the left prefrontal cortex greater habituation to happy vs fearful stimuli was evident, suggesting devotion of sustained neural resources for processing of threat vs safety signals. In the amygdala, significantly greater habituation was observed on the right compared to the left. In contrast, the left amygdala was significantly more activated than the right to the contrast of fear vs happy. We Speculate that the right amygdala is part of a dynamic emotional stimulus detection system, while the left is specialized for sustained stimulus evaluations. NeuroReport 12:379-383 (C) 2001 Lippincott Williams & Wilkins.
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