期刊
JOURNAL OF BIOMEDICAL OPTICS
卷 20, 期 8, 页码 -出版社
SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.JBO.20.8.086004
关键词
photoacoustic imaging; laser-generated ultrasound; multimodality imaging
资金
- Ministry of Science and Technology [100-2221-E-002-146-MY3, 103-2811-8-002-001, 102-2221-E-002-065-MY3]
Conventional ultrasound (US) and photoacoustic (PA) multimodality imaging require the use of a US pulse for US data acquisition and a laser pulse for PA data acquisition. We propose a method for concurrent US and PA data acquisition with a single-laser pulse. A light-absorbing multilayer film that can generate a US pulse based on the thermoelastic effect is used. The selection of appropriate layer thickness, interlayer spacing, and absorption coefficient allows the spectral characteristics of the generated US signal to be adjusted so that it does not overlap with the spectrum of the PA signal generated by the light transmitting through the layer. Thus, the US signal and the PA signal can be generated, received, and separated by using a single-laser pulse combined with spectral filtering. This method is demonstrated using a multilayer film that generates US signals with a center frequency of 24.2 MHz and fractional bandwidth of 26.8%. The synthetic-aperture focusing technique is applied to improve the lateral resolution and the signal-to-noise ratio. A cyst-like phantom and a film phantom were used to demonstrate the feasibility of this method of concurrent PA-US imaging using single-laser pulses. (C) 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据