期刊
FRONTIERS IN BIOSCIENCE-LANDMARK
卷 6, 期 -, 页码 D388-D405出版社
FRONTIERS IN BIOSCIENCE INC
DOI: 10.2741/Goldberg
关键词
triglyceride; chylomicrons; heparin; proteoglycans; hyperlpidemai; review
Lipoprotein lipase (LpL) is the primary enzyme responsible for conversion of lipoprotein triglyceride into free fatty acids and monoglyderides. This permits their uptake into muscle and adipose. The roles of this enzyme in normal and altered physiology are reviewed. In addition, the relationship of LpL activity and genetic variations of LpL and human disease are summarized.Lipoprotein lipase (LpL) is the primary enzyme responsible for conversion of lipoprotein triglyceride into free fatty acids and monoglyderides. This permits their uptake into muscle and adipose. The roles of this enzyme in normal and altered physiology are reviewed. In addition, the relationship of LpL activity and genetic variations of LpL and human disease are summarized.
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