期刊
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS
卷 1799, 期 3-4, 页码 337-351出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbagrm.2010.01.004
关键词
Viral chromatin; Methylation; Silencing suppression; AL2 protein; L2 protein
资金
- NSF [MCB-0743261]
- National Research Initiative of the USDA [2004-35301-14508]
It is well-established that plants use cytoplasmic, post-transcriptional gene silencing (PTGS) as a defense against RNA viruses and DNA virus transcripts. More recently, it has become clear that small RNA-directed methylation leading to transcriptional gene silencing (TGS) is also used as a defense against DNA virus chromatin. Here we use the DNA-containing geminiviruses as models to discuss what is currently known about both types of antiviral silencing, and viral suppression of PTGS and TGS as a counterdefense. (C) 2010 Elsevier B.V. All rights reserved.
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