期刊
PEDIATRIC INFECTIOUS DISEASE JOURNAL
卷 20, 期 3, 页码 235-239出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00006454-200103000-00002
关键词
immunologic memory and Haemophilus disease
资金
- NCRR NIH HHS [RR01271] Funding Source: Medline
- NIAID NIH HHS [AI45642, AI25008] Funding Source: Medline
Considerable evidence indicates that both anticapsular antibody and immunologic memory play a role in immunity to Haemophilus influenzae type b (Hib) disease. The efficacy of memory (or antibody) cannot be expected to be 100%; therefore some individuals may develop invasive disease despite their having been naturally primed. The proportion of cases of H. influenzae type b disease with evidence of immunologic memory is related to both the efficacy of memory in preventing disease and the age-related prevalence of memory in the population. The task is to discern the relative contributions of antibody and memory in conferring protection and to determine the extent to which natural exposure and vaccination establish these two effector mechanisms.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据