期刊
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
卷 1778, 期 9, 页码 1735-1756出版社
ELSEVIER
DOI: 10.1016/j.bbamem.2007.07.015
关键词
secretion; SecA; SecY; twin arginine; Tat
资金
- Council for Chemical Sciences of the Netherlands Organization for Scientific Research
- Dutch Organization for the Advancement of Scientific Research
- NanoNed
- Dutch Ministry of Economic Affairs (to A.J.M.D.)
- Deutsche Forschungsgemeinschaft
- state Sachsen-Anhalt (Exzellenzcluster Biowissenschaften)
In bacteria, two major pathways exist to secrete proteins across the cytoplasmic membrane. The general Secretion route, termed Sec-pathway, catalyzes the transmembrame translocation of proteins in their unfolded conformation, whereupon they fold into their native structure at the trans-side of the membrane. The Twin-arginine translocation pathway, termed Tat-pathway, catalyses the translocation of secretory proteins in their folded state. Although the targeting signals that direct secretory proteins to these pathways show a high degree of similarity, the translocation mechanisms and translocases involved are vastly different. (C) 2007 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据