期刊
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
卷 1817, 期 10, 页码 1823-1832出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbabio.2012.03.017
关键词
Na+-NQR; Primary sodium pump; NADH:quinone oxidoreductase; Na+ translocation; Bacterial energy transduction
资金
- National Science Foundation [MCB 1052234]
- National Institutes of Health [GM 060036]
- Div Of Molecular and Cellular Bioscience
- Direct For Biological Sciences [1052234] Funding Source: National Science Foundation
Na+-NQR is a unique energy-transducing complex, widely distributed among marine and pathogenic bacteria. It converts the energy from the oxidation of NADH and the reduction of quinone into an electrochemical Na+-gradient that can provide energy for the cell. Na+-NQR is not homologous to any other respiratory protein but is closely related to the RNF complex. In this review we propose that sodium pumping in Na+-NQR is coupled to the redox reactions by a novel mechanism, which operates at multiple sites, is indirect and mediated by conformational changes of the protein. This article is part of a Special Issue entitled: 17th European Bioenergetics Conference (EBEC 2012). (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据