期刊
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
卷 104, 期 2, 页码 465-475出版社
WILEY
DOI: 10.1002/jbm.a.35582
关键词
bone; carbon nanotube; remodeling; strain energy; microcracking
资金
- Alberta Innovates Technology Futures (AITF, Canada) through AITF New Faculty Programme
- Alberta Innovates Health Solutions (AIHS, Canada) through AIHS Sustainability Programme
- Natural Sciences and Engineering Research Council (NSERC, Canada) through NSERC
Beside their biochemical properties, the exceptional mechanical characteristics of carbon nanotubes (CNTs) suggested growing a reinforced composite material very similar to natural bone in structure and chemical composition, but significantly stronger and stiffer. This is where biomechanical considerations portray themselves to justify the need for further investigations, in order to verify the applicability of CNTs as scaffolds that may ease bone regeneration and simultaneously raise its mechanical strength and durability. This research, using several modeling approaches, attempts to look at some of the mechanical changes likely to take place in the promised artificial tissue, while considering the relationships between mechanical and living functions of bone, particularly the remodeling process. Results suggest that notwithstanding the significant improvements induced to the mechanical behavior of the artificial tissue, applications of such stiff inclusions as CNTs in reinforcing the material of bone may detrimentally change the thresholds of mechanical stimuli that are essential for the initiation and resumption of the bone remodeling process. (c) 2015 Wiley Periodicals, Inc.
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