4.4 Article

Usefulness of a narrow-band reflectance spectrophotometer in evaluating effects of depigmenting treatment

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AESTHETIC PLASTIC SURGERY
卷 25, 期 2, 页码 129-133

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SPRINGER-VERLAG
DOI: 10.1007/s002660010109

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depigmenting treatment; retinoic acid aqueous gel; senile lentigines; nevus spilus

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As a depigmenting treatment, combined topical applications of all-trans retinoic acid (atRA) aqueous gel and 5% hydroquinone, 7% lactic acid ointment were used for Oriental patients with hyperpigmented skin lesions such as senile lentigines and nevus spilus. A narrow-band reflectance spectrophotometer and a tristimulus colorimeter were used to evaluate objectively the intensity of pigmentation and erythema at each clinical visit. L*, a*, and b* values measured with a tristimulus colorimeter (Chroma Meter CR-300) enabled the evaluation of erythema but not pigmentation. On the other hand, the melanin and hemoglobin values measured with a narrow-band reflectance spectrophotometer (Mexameter MX-16) expressed both erythema and pigmentation well. It was revealed that, in our bleaching protocol, the narrow-band reflectance spectrophotometer was quite useful for estimating accurately the intensity of pigmentation and erythema and determining the best time point for the cessation of atRA treatment.

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