4.5 Review

Transcriptional regulation of the human apolipoprotein genes

期刊

FRONTIERS IN BIOSCIENCE-LANDMARK
卷 6, 期 -, 页码 D456-D504

出版社

BIOSCIENCE RESEARCH INST-BRI
DOI: 10.2741/Zannis

关键词

lipoproteins; apoproteins; apoA-I; apoA-II; apoA-IV; apoB; apoCI; apoCII; apoCIII; apoE; basal transcription complex; transcription factors; HNF-4; hormone nuclear receptors (PPAR, RXR, RAR, T3R beta); SP1; SREBP-1; SREBP-2; USF; ATF-2; Jun; SMAD; promoters; enhancers; transcriptional activation; transcriptional synergism; tissue-specific transcription; transgenic mice; signaling pathways (NF kappa B, SAPK/JNK, MAPK)

资金

  1. NHLBI NIH HHS [HL33952] Funding Source: Medline

向作者/读者索取更多资源

This review provides experiments and putative mechanisms which underlie the transcription of the human apolipoprotein genes in vitro and in vivo. Summarized below are the key findings for individual genes and gene clusters.

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