期刊
SCIENCE
卷 291, 期 5510, 页码 1969-1972出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.291.5510.1969
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资金
- NIDCD NIH HHS [Z01-DC-00043-03] Funding Source: Medline
We used a twin study to investigate the genetic and environmental contributions to differences in musical pitch perception abilities in humans. We administered a Distorted Tunes Test (DTT), which requires subjects to judge whether simple popular melodies contain notes with incorrect pitch, to 136 monozygotic twin pairs and 148 dizygotic twin pairs. The correlation of DTT scores between twins was estimated at 0.67 for monozygotic pairs and 0.44 for dizygotic pairs. Genetic model-fitting, techniques supported an additive genetic model, with heritability; estimated at 0.71 to 0.80, depending on how subjects were categorized, and with no effect of shared environment. DTT scores were only weakly correlated with measures of peripheral hearing. This suggests that variation in musical pitch recognition is primarily due to highly heritable differences in auditory functions not tested by conventional audiologic methods.
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