期刊
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
卷 225, 期 1-2, 页码 187-193出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0304-8853(00)01256-7
关键词
magnetic drug targeting; mitoxantrone; magnetic particles; rabbit; cancer treatment; coated ferrofluids; starch; intraarterial administration; in vivo targeting; ferrofluid; histology; X-ray imaging; MR imaging; digital subtraction angiography; DSA; VX-2 squamous cell carcinoma; tumor model; chemotherapy
Ferrofluids coated with starch polymers can be used as biocompatible carriers. Bound to medical drugs, such magnetic particles can be enriched in a desired body compartment using an external magnetic field. In the present study, we confirm the enrichment of ferrofluids in tumor tissue using histological investigations and conventional imaging techniques, i.e. X-ray and MRI. (C) 2001 Elsevier Science B.V. All rights reserved.
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