期刊
MECHANISMS OF DEVELOPMENT
卷 102, 期 1-2, 页码 267-269出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0925-4773(01)00309-4
关键词
expression pattern; Na-K-2Cl-cotransporter NKCC1; mouse development
Here we describe the expression pattern of the Na-K-2Cl-cotransporter NKKC1 during embryonal and early postnatal mouse development. During early stages hybridization signals were detected over single cells of the developing neuroepithelia, whereas the neuroepithelium of the basal telencephalon was labeled continuously. With ongoing differentiation a distinct pattern of hybridization became apparent, which switched from a neuronal to a more glial pattern in the adult. Outside the nervous system NKCC1 transcripts were present in many organs and were mostly confined to epithelia. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
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