期刊
JOURNAL OF VIROLOGY
卷 75, 期 8, 页码 3696-3705出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.75.8.3696-3705.2001
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The G and P genotypes of 3,601 rotavirus strains collected in the United Kingdom between 1995 and 1999 were determined (M. Iturriza-Gomara et al., J. Clin. Microbiol. 38:4394-4401, 2000), In 95.4% of the strains the most common G and P combinations, G1P[8], G2P[4], G3P[8], and G4P[8], were found. A small but significant number (2%) of isolates from the remaining strains were reassortants of the most common cocirculating strains, e.g,, G1P[4] and G2P[8], Rotavirus G9P[6] and G9P[8] strains, which constituted 2.7% of all viruses, were genetically closely related in their G components, but the P components of the G9P[8] strains mere very closely related to those of cocirculating strains of the more common G types (G1, G3, and G4). In conclusion, genetic interaction by reassortment among cocirculating rotaviruses is not a rare event and contributes significantly to their overall diversity.
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