Application of magnetic liposomes for magnetically guided transport of muscle relaxants and anti-cancer photodynamic drugs

Magnetic liposomes containing submicron-sized ferromagnetic particles were prepared encapsulating the muscle relaxant drugs, diadony or diperony, for local anesthesia. Alternatively, metal phthalocyanines (Photosense or Teraphthal), sensitizers for photodynamic or catalytic cancer therapy were loaded into the magnetic liposomes. Animal trials demonstrated successful magnetically guided transport of the drug-loaded liposomes. (C) 2001 Elsevier Science B.V. All rights reserved.