期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 131, 期 4, 页码 321-324出版社
CONSULTANTS BUREAU
DOI: 10.1023/A:1017983615183
关键词
lipoproteins; phospholipids; lipoprotein lipase; hepatic lipase
We studied phospholipid composition of high-density lipoproteins in patients with normo- and hypertriglyceridemia treated with various hypolipidemic preparations (simvastatin and fenofibrate). Both preparations changed phospholipid composition of high-density lipoproteins and improved their functional activity. The differences in the phospholipid composition of high-density lipoproteins were probably related to lipolysis of triglyceride-rich lipoproteins catalyzed by lipoprotein lipase and, in particular, hepatic lipase.
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