4.3 Article

A novel antivirally active fucan sulfate derived from an edible brown alga, Sargassum horneri

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CHEMICAL & PHARMACEUTICAL BULLETIN
卷 49, 期 4, 页码 484-485

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PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.49.484

关键词

fucan sulfate; antiviral activity; Sargassum horneri; brown alga; sulfated polysaccharide

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A novel fucan sulfate (Hor-1) was isolated from the hot water extract of an edible brown alga, Sargassum horneri (Turner) C, AGARDH, The fucan sulfate was revealed to have sugar linkage types, sulfate content and uronic acid content different from those of sodium hornan (Na-HOR), another fucan sulfate isolated from this alga, However, it exhibited inhibitory activity against replication of herpes simplex virus type 1 with similar potency to Na-HOR.

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