期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 45, 期 4, 页码 1312-1314出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.45.4.1312-1314.2001
关键词
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High doses of Listeria monocytogenes overcome the ability of a normal mouse to control the infection, due to massive bacterial replication. Treatment with an anti-interleukin 10 (IL-10) receptor monoclonal antibody prevented the fatal course of infection with high doses of bacteria. This work shows that blocking the receptor for IL-10 may have useful therapeutic applications.
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