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Dynamic concentration of motors in microtubule arrays

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PHYSICAL REVIEW LETTERS
卷 86, 期 14, 页码 3192-3195

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AMERICAN PHYSICAL SOC
DOI: 10.1103/PhysRevLett.86.3192

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We present experimental and theoretical studies of the dynamics of molecular motors in microtubule arrays and asters. By solving a convection-diffusion equation we find that the density profile of motors in a two-dimensional aster is characterized by continuously varying exponents. Simulations are used to verify the assumptions of the continuum model. We observe the concentration profiles of kinesin moving in quasi-two-dimensional artificial asters by fluorescent microscopy and compare with our theoretical results.

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