期刊
ORGANIC LETTERS
卷 3, 期 8, 页码 1189-1192出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol015648a
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资金
- NCRR NIH HHS [S10 RR10444] Funding Source: Medline
- NIGMS NIH HHS [GM58822] Funding Source: Medline
Protein and peptide conjugates such as glycopeptides, prenylated peptides, and lipopeptides play essential roles in biology, A rapid and convergent entry into a variety of these compounds is described, The methodology involves the introduction of a dehydroalanine into peptides and subsequent chemoselective conjugate addition of an appropriate thiolate nucleophile, including farnesylthiolate or thioglycosides.
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