We perform the next-to-leading-order QCD analysis of the world data on inclusive deep-inelastic-scattering cross sections of charged leptons off the proton and deuterium targets. The parton distributions, the value of strong-coupling constant alpha (s), and the twist-4 contributions to the structure functions F-2 and F-L are extracted with a complete account of the correlations of data points due to the systematic errors. The sensitivity of the alpha (s) value and the high-twist contribution to the procedures of accounting for the systematic errors are studied. The impact of theoretical uncertainties on the value of alpha (s) and on the parton distributions is analyzed. The obtained value of the strong-coupling constant taking into account these uncertainties is alpha (s)(M-Z) = 0.1165 +/-0.0017 (stat+syst) (+0.0026)(-0.0034)(theor). The uncertainties of parton-parton luminosities for the Fermilab and CERN LHC colliders are estimated.
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