期刊
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
卷 114, 期 2, 页码 151-159出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0166-6851(01)00246-8
关键词
acidocalcisome; calcium; intracellular parasites; Leishmania; malaria; Toxoplasma gondii; Trypanosoma brucei; Trypanosoma cruzi; volutin granule
资金
- NIAID NIH HHS [AI-23259, AI-43614] Funding Source: Medline
The acidocalcisome is an electron-dense acidic organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations. Its limiting membrane possesses a number of pumps and exchangers for the uptake and release of these elements. The acidocalcisome does not belong to the endocytic pathway and may represent a branch of the secretory pathway in trypanosomatids and apicomplexan parasites. The acidocalcisome is possibly involved in polyphosphate and cation storage and in adaptation of these microoganisms to environmental stress. (C) 2001 Elsevier Science B.V. All rights reserved.
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