期刊
BIOCHEMICAL SOCIETY TRANSACTIONS
卷 39, 期 -, 页码 910-916出版社
PORTLAND PRESS LTD
DOI: 10.1042/BST0390910
关键词
Alzheimer's disease; amyloid beta-peptide; complement system; disease modelling; genome-wide association study (GWAS); lipid metabolism
资金
- Alzheimer's Research UK
- Wellcome Trust/Medical Research Council
- MRC [MC_G1000735, G0701075] Funding Source: UKRI
- Alzheimers Research UK [ART-PG2010-1, ART-PPG2011A-14] Funding Source: researchfish
- Medical Research Council [MC_G1000735, G0701075] Funding Source: researchfish
- Parkinson's UK [G-0907] Funding Source: researchfish
In the present review, we look back at the recent history of GWAS (genome-wide association studies) in AD (Alzheimer's disease) and integrate the major findings with current knowledge of biological processes and pathways. These topics are essential for the development of animal models, which will be fundamental to our complete understanding of AD.
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