期刊
BIOCHEMICAL SOCIETY TRANSACTIONS
卷 37, 期 -, 页码 991-996出版社
PORTLAND PRESS LTD
DOI: 10.1042/BST0370991
关键词
dynein; lipid droplet; microtubule; motility; perilipin/adipose differentiation-related protein (ADRP)/47 kDa tail-interacting protein (TIP47) protein (PAT protein)
资金
- National Institutes of Health [GM64687]
Lipid droplets are intracellular organelles that play central roles in lipid metabolism. in many cells, lipid droplets undergo active motion, typically along microtubules. This motion has been proposed to aid growth and breakdown of droplets, to allow net transfer of nutrients from sites of synthesis to sites of need and to deliver proteins and lipophilic signals. This review summarizes the current understanding of where, why and how lipid droplets move.
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