期刊
BIOCHEMICAL SOCIETY TRANSACTIONS
卷 36, 期 -, 页码 1194-1196出版社
PORTLAND PRESS LTD
DOI: 10.1042/BST0361194
关键词
antimir; antagomir; microRNA (miRNA); RNA-induced silencing complex (RISC); target prediction program
资金
- BBSRC (Biotechnology and Biological Sciences Research Council)
- NERC (Natural Environment Research Council)
- European Union
- BBSRC [BB/E024866/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/E024866/1] Funding Source: researchfish
- Natural Environment Research Council [NE/C508226/1] Funding Source: researchfish
miRNAs (microRNAs) are recently discovered regulators of gene expression. They target mRNAs that contain partially complementary sites to the miRNA. The level of complementarity is different between target site-miRNA pairs, and finding target genes has proved to be a bigger challenge than expected. The present paper reviews the different approaches to predict and experimentally identify genes targeted by miRNAs.
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