4.6 Article

β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Endocrinology & Metabolism

GPR40 agonists for the treatment of type 2 diabetes: life after 'TAKing' a hit

A. D. Mancini et al.

DIABETES OBESITY & METABOLISM (2015)

Article Cell Biology

Recent developments in biased agonism

James W. Wisler et al.

CURRENT OPINION IN CELL BIOLOGY (2014)

Article Endocrinology & Metabolism

β-Arrestin2 plays a key role in the modulation of the pancreatic beta cell mass in mice

Magalie A. Ravier et al.

DIABETOLOGIA (2014)

Article Biochemistry & Molecular Biology

Allosteric Modulation of M1 Muscarinic Acetylcholine Receptor Internalization and Subcellular Trafficking

Holly R. Yeatman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875

Ankita Srivastava et al.

NATURE (2014)

Article Biotechnology & Applied Microbiology

OPINION Signalling bias in new drug discovery: detection, quantification and therapeutic impact

Terry Kenakin et al.

NATURE REVIEWS DRUG DISCOVERY (2013)

Review Endocrinology & Metabolism

The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?

Arturo D. Mancini et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)

Article Chemistry, Medicinal

AMG 837: A potent, orally bioavailable GPR40 agonist

Jonathan B. Houze et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Review Biochemistry & Molecular Biology

Restructuring G-Protein-Coupled Receptor Activation

Martin Audet et al.

Review Pharmacology & Pharmacy

Probing Heterotrimeric G Protein Activation: Applications to Biased Ligands

Colette Denis et al.

CURRENT PHARMACEUTICAL DESIGN (2012)

Review Biochemistry & Molecular Biology

Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling

Arun K. Shukla et al.

TRENDS IN BIOCHEMICAL SCIENCES (2011)

Article Multidisciplinary Sciences

M3-muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1

Kok Choi Kong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Chemistry, Medicinal

Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist

Nobuyuki Negoro et al.

ACS MEDICINAL CHEMISTRY LETTERS (2010)

Article Multidisciplinary Sciences

β-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic β cells

Noriyuki Sonoda et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

Identification of residues important for agonist recognition and activation in GPR40

Chi Shing Sum et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Pharmacology & Pharmacy

β-arrestin-biased ligands at seven-transmembrane receptors

Jonathan D. Violin et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2007)

Article Endocrinology & Metabolism

GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo

Martin G. Latour et al.

DIABETES (2007)

Article Biochemistry & Molecular Biology

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes

Celine Gales et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Role of GPR40 in fatty acid action on the β cell line INS-1E

H Shapiro et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Article Multidisciplinary Sciences

Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2

HJ Wei et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

CP Briscoe et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Medicine, Research & Experimental

Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets

K Maedler et al.

JOURNAL OF CLINICAL INVESTIGATION (2002)