4.6 Article

Reaction of Hydrogen Sulfide with Disulfide and Sulfenic Acid to Form the Strongly Nucleophilic Persulfide

期刊

JOURNAL OF BIOLOGICAL CHEMISTRY
卷 290, 期 45, 页码 26866-26880

出版社

ELSEVIER
DOI: 10.1074/jbc.M115.672816

关键词

-

资金

  1. Comision Sectorial de Investigacion Cientifica (Universidad de la Republica)
  2. L'Oreal-UNESCO, Uruguay
  3. Friedrich-Alexander University of Erlangen-Nuremberg (MRIC)
  4. Agencia Nacional de Investigacion e Innovacion
  5. PEDECIBA, Uruguay

向作者/读者索取更多资源

Background: Hydrogen sulfide (H2S) modulates physiological processes in mammals. Results: The reactivity of H2S toward disulfides (RSSR) and albumin sulfenic acid (RSOH) to form persulfides (RSSH) was assessed. Conclusion: H2S is less reactive than thiols. Persulfides have enhanced nucleophilicity. Significance: This kinetic study helps rationalize the contribution of the reactions with oxidized thiol derivatives to H2S biology.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据