期刊
JOURNAL OF MAGNETIC RESONANCE IMAGING
卷 13, 期 5, 页码 757-760出版社
WILEY
DOI: 10.1002/jmri.1105
关键词
MRI; bone marrow; diffusion-weighted EPI; marrow cellularity; ADC
This study was performed to determine if there is a relationship between apparent diffusion coefficient (ADC) and cellularity of bone marrow of the posterior ilium. Four groups of various marrow cellularity underwent diffusion-weighted echo-planar imaging: 1) adults with normal hypocellularity (21 patients); 2) adults with normal normo-cellularity (13 patients); 3) young children with normal hypercellularity (5 patients); and 4) adults with lymphoma-related hypercellularity (3 patients). In all adults, marrow cellularity was confirmed by uni-or bilateral bone marrow biopsies. In children, the iliac marrow was presumed hypercellular because of their ages. A total of 66 ADC values of bone marrow calculated from diffusion-weighted Images with b-values of 30 and 300 seconds/mm(2) was evaluated. Hypercellular marrow (normal and lymphoma-related) showed the highest mean ADC, and hypocellular the lowest ADC. Statistically significant differences were found between three groups of normal marrow: hypocellular, normocellular, and hypercellular. There Is a positive correlation between ADC and cellularity of bone marrow. (C) 2001 Wiley-Liss, Inc.
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