期刊
EMBO JOURNAL
卷 20, 期 9, 页码 2140-2151出版社
WILEY
DOI: 10.1093/emboj/20.9.2140
关键词
cell compartmentalization; functional genomics; nuclear bodies; RBCC; tripartite motif
资金
- Telethon [TGM06S01] Funding Source: Medline
A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM), A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.
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