期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 26, 期 5, 页码 310-317出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0968-0004(01)01805-9
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Glucose not only serves as a nutrient but also exerts many hormone-like regulatory effects in a wide variety of eukaryotic cell types. Recently, interest in identifying general mechanisms and principles used to sense the presence of glucose has significantly increased and promising advances have been made: in yeast, the first proteins with an apparently specific function in glucose detection have been discovered; in plant cells, there is increasing evidence for a diverse array of glucose-induced signalling mechanisms; and in mammals, glucose-sensing phenomena have turned out to be much more widespread than just in the well-known example of pancreatic beta cells.
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