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Akinori Eiyama et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
Agne Kazlauskaite et al.
EMBO REPORTS (2015)
Phosphorylated ubiquitin chain is the genuine Parkin receptor
Kei Okatsu et al.
JOURNAL OF CELL BIOLOGY (2015)
Unconventional PINK1 localization to the outer membrane of depolarized mitochondria drives Parkin recruitment
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JOURNAL OF CELL SCIENCE (2015)
Mechanism of phospho-ubiquitin-induced PARKIN activation
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NATURE (2015)
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson's Disease
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NEURON (2015)
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
Agne Kazlauskaite et al.
BIOCHEMICAL JOURNAL (2014)
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
Lesley A. Kane et al.
JOURNAL OF CELL BIOLOGY (2014)
Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
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MOLECULAR CELL (2014)
Phosphorylation of Mitochondrial Polyubiquitin by PINK1 Promotes Parkin Mitochondrial Tethering
Kahori Shiba-Fukushima et al.
PLOS GENETICS (2014)
PINK1 is degraded through the N-end rule pathway
Koji Yamano et al.
AUTOPHAGY (2013)
Structure of the human Parkin ligase domain in an autoinhibited state
Tobias Wauer et al.
EMBO JOURNAL (2013)
Parkin-catalyzed Ubiquitin-Ester Transfer Is Triggered by PINK1-dependent Phosphorylation
Masahiro Iguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
Michael Lazarou et al.
JOURNAL OF CELL BIOLOGY (2013)
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
Shireen A. Sarraf et al.
NATURE (2013)
Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
Jean-Francois Trempe et al.
SCIENCE (2013)
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
B. E. Riley et al.
NATURE COMMUNICATIONS (2013)
Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
Michael Lazarou et al.
DEVELOPMENTAL CELL (2012)
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
Andrew W. Greene et al.
EMBO REPORTS (2012)
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
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SCIENTIFIC REPORTS (2012)
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
Chandana Kondapalli et al.
OPEN BIOLOGY (2012)
Autoregulation of Parkin activity through its ubiquitin-like domain
Viduth K. Chaugule et al.
EMBO JOURNAL (2011)
PINK1 cleavage at position A103 by the mitochondrial protease PARL
Emma Deas et al.
HUMAN MOLECULAR GENETICS (2011)
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
Nickie C. Chan et al.
HUMAN MOLECULAR GENETICS (2011)
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
Cathrin Meissner et al.
JOURNAL OF NEUROCHEMISTRY (2011)
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
Dawn M. Wenzel et al.
NATURE (2011)
Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations
Helen I. Woodroof et al.
OPEN BIOLOGY (2011)
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
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JOURNAL OF CELL BIOLOGY (2010)
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
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JOURNAL OF CELL BIOLOGY (2010)
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
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JOURNAL OF CELL BIOLOGY (2010)
An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli
Travis S. Young et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
Derek P. Narendra et al.
PLOS BIOLOGY (2010)
Ubiquitin C-Terminal Electrophiles Are Activity-Based Probes for Identification and Mechanistic Study of Ubiquitin Conjugating Machinery
Kerry Routenberg Love et al.
ACS CHEMICAL BIOLOGY (2009)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin
SR Sriram et al.
HUMAN MOLECULAR GENETICS (2005)
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BIOINFORMATICS (2004)
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MOLECULAR AND CELLULAR BIOLOGY (2004)
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SCIENCE (2004)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
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