期刊
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
卷 56, 期 3, 页码 P134-P140出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/geronb/56.3.P134
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The New England Centenarian Study is a population-based study of all centenarians in B towns near Boston, MA. Age was confirmed for 43 centenarians all alive on a designated date. To determine prevalence of dementia in centenarians, the authors analyzed neuropsychological, medical, and functional status data for 34 (79%) of the centenarians. Definition of dementia was based on the Consortium to Establish a Registry for Alzheimer's Disease criteria, and a Clinical Dementia Rating (CDR) score was formulated for each participant. Seven (21%) had no dementia (CDR score 0), and an additional 4 (12%) were assigned a CDR score of 0.5, uncertain or deferred diagnosis. The remaining 22 (64%) had at least some degree of dementia, The authors calculated Barthel Index scores to determine ability to perform activities of daily living. There was a statistically significant correlation between CDR stores and Barthel Index scores (r = -0.73), Correlation was strongest for those with no or severe dementia, with the greatest range of function measured among those with moderate dementia.
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