相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Chromatin dynamics: Interplay between remodeling enzymes and histone modifications
Sarah G. Swygert et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2014)
A Cell-Permeable Ester Derivative of the JmjC Histone Demethylase Inhibitor IOX1
Rachel Schiller et al.
CHEMMEDCHEM (2014)
Histone variants: dynamic punctuation in transcription
Christopher M. Weber et al.
GENES & DEVELOPMENT (2014)
Pan-Histone Demethylase Inhibitors Simultaneously Targeting Jumonji C and Lysine-Specific Demethylases Display High Anticancer Activities
Dante Rotili et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
HIF-1-Dependent Induction of Jumonji Domain-Containing Protein (JMJD) 3 under Hypoxic Conditions
Ho-Youl Lee et al.
MOLECULES AND CELLS (2014)
Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
Gregg L. Semenza
Annual Review of Pathology-Mechanisms of Disease (2013)
Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase
Elena M. Sanchez-Fernandez et al.
BIOCHEMICAL JOURNAL (2013)
Pan-genomic binding of hypoxia-inducible transcription factors
Johannes Schoedel et al.
BIOLOGICAL CHEMISTRY (2013)
Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis
Yu-Ching Teng et al.
CANCER RESEARCH (2013)
Mechanisms and Functions of ATP-Dependent Chromatin-Remodeling Enzymes
Geeta J. Narlikar et al.
CELL (2013)
The NuRD architecture
Hillary F. Allen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2013)
The histone H3-K27 demethylase Utx regulates HOX gene expression in Drosophila in a temporally restricted manner
Oemer Copur et al.
DEVELOPMENT (2013)
Epigenetic Regulation of Adipogenesis by PHF2 Histone Demethylase
Yosuke Okuno et al.
DIABETES (2013)
Identification of Small Molecule Inhibitors of Jumonji AT-rich Interactive Domain 1B (JARID1B) Histone Demethylase by a Sensitive High Throughput Screen
Joyce Sayegh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling
Klaus W. Wagner et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
Peter J. Ratcliffe
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Regulation of nucleosome dynamics by histone modifications
Gabriel E. Zentner et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Novel insights into histone modifiers in adipogenesis
Yosuke Okuno et al.
ADIPOCYTE (2013)
Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases
Esther C. Y. Woon et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Histone demethylase JMJD5 is essential for embryonic development
Sangphil Oh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Chromatin as an oxygen sensor and active player in the hypoxia response
Andrew Melvin et al.
CELLULAR SIGNALLING (2012)
Making sense of transcribing chromatin
Tom Owen-Hughes et al.
CURRENT OPINION IN CELL BIOLOGY (2012)
Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases
WeiShen Aik et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2012)
UTX, a Histone H3-Lysine 27 Demethylase, Acts as a Critical Switch to Activate the Cardiac Developmental Program
Seunghee Lee et al.
DEVELOPMENTAL CELL (2012)
Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases
Nathan R. Rose et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Histone H3 Lysine 36 Methylation Targets the Isw1b Remodeling Complex to Chromatin
Vicki E. Maltby et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Histone Demethylase UTX and Chromatin Remodeler BRM Bind Directly to CBP and Modulate Acetylation of Histone H3 Lysine 27
Feng Tie et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
Joshua C. Black et al.
MOLECULAR CELL (2012)
Novel mutations target distinct subgroups of medulloblastoma
Giles Robinson et al.
NATURE (2012)
Dissecting the genomic complexity underlying medulloblastoma
David T. W. Jones et al.
NATURE (2012)
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
Laurens Kruidenier et al.
NATURE (2012)
The mutational landscape of lethal castration-resistant prostate cancer
Catherine S. Grasso et al.
NATURE (2012)
The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C
X. Niu et al.
ONCOGENE (2012)
Histone Demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Protein Nuclear Stabilization
Chibawanye I. Ene et al.
PLOS ONE (2012)
Microarray Comparative Genomic Hybridization Detection of Copy Number Changes in Desmoplastic Melanoma and Malignant Peripheral Nerve Sheath Tumor
Jennifer G. Pryor et al.
AMERICAN JOURNAL OF DERMATOPATHOLOGY (2011)
The Testis-Enriched Histone Demethylase, KDM4D, Regulates Methylation of Histone H3 Lysine 9 During Spermatogenesis in the Mouse but Is Dispensable for Fertility
Naoki Iwamori et al.
BIOLOGY OF REPRODUCTION (2011)
KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia
Jin He et al.
BLOOD (2011)
Hypoxia causes epigenetic gene regulation in macrophages by attenuating Jumonji histone demethylase activity
Michaela Tausendschoen et al.
CYTOKINE (2011)
Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development
Brenda J. Curtis et al.
DEVELOPMENTAL BIOLOGY (2011)
The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice
Qing-Jun Zhang et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly
Tsuyoshi Fukuda et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2011)
The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH
Andrew Melvin et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Role of Androgen Receptor and Associated Lysine-Demethylase Coregulators, LSD1 and JMJD2A, in Localized and Advanced Human Bladder Cancer
Eric C. Kauffman et al.
MOLECULAR CARCINOGENESIS (2011)
FGF-2 Regulates Cell Proliferation, Migration, and Angiogenesis through an NDY1/KDM2B-miR-101-EZH2 Pathway
Filippos Kottakis et al.
MOLECULAR CELL (2011)
Hypoxia-induced methylation of a pontin chromatin remodeling factor
Jason S. Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis
Lei Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase
Xue Zhou et al.
CANCER RESEARCH (2010)
Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8
Joel A. Yates et al.
FEBS LETTERS (2010)
The histone demethylase Dmel\Kdm4A controls genes required for life span and male-specific sex determination in Drosophila
Meridith T. Lorbeck et al.
GENE (2010)
KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development
Yu-ichi Tsukada et al.
GENES & DEVELOPMENT (2010)
Phenotypic annotation of the mouse X chromosome
Brian J. Cox et al.
GENOME RESEARCH (2010)
The Role of Histone Modifications and Variants in Regulating Gene Expression in Breast Cancer
Mathieu Dalvai et al.
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2010)
Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1 alpha Enhances Hypoxic Gene Expression and Tumor Growth
Adam J. Krieg et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway
Shinya Hayami et al.
MOLECULAR CANCER (2010)
A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation
Daniela Kleine-Kohlbrecher et al.
MOLECULAR CELL (2010)
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
Jason S. Lee et al.
MOLECULAR CELL (2010)
Regulation of Androgen-Responsive Transcription by the Chromatin Remodeling Factor CHD8
Tushar Menon et al.
MOLECULAR ENDOCRINOLOGY (2010)
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
Takashi Satoh et al.
NATURE IMMUNOLOGY (2010)
Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65
Tao Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications
Catherine A. Musselman et al.
BIOCHEMICAL JOURNAL (2009)
LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer
Yan Wang et al.
CELL (2009)
Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
Francesca De Santa et al.
EMBO JOURNAL (2009)
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence
Karl Agger et al.
GENES & DEVELOPMENT (2009)
Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice
Takeshi Inagaki et al.
GENES TO CELLS (2009)
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns
Michael P. Schnetz et al.
GENOME RESEARCH (2009)
SWI/SNF Regulates the Cellular Response to Hypoxia
Niall S. Kenneth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Quantitative analysis of chromatin compaction in living cells using FLIM-FRET
David Lleres et al.
JOURNAL OF CELL BIOLOGY (2009)
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger
Gang G. Wang et al.
NATURE (2009)
Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
Keisuke Tateishi et al.
NATURE (2009)
Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer
G. Liu et al.
ONCOGENE (2009)
Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus
Alexandros Tzatsos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Hypoxia upregulates the histone demethylase JMJDIA via HIF-1
Sven Wellmann et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α
Patrick J. Pollard et al.
BIOCHEMICAL JOURNAL (2008)
KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state
David Frescas et al.
CELL CYCLE (2008)
Mucosa-Associated Lymphoid Tissue Lymphoma: Novel Translocations Including Rearrangements of ODZ2, JMJD2C, and CNN3
Ursula Vinatzer et al.
CLINICAL CANCER RESEARCH (2008)
dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing
Anna Lagarou et al.
GENES & DEVELOPMENT (2008)
The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF
Sophie Beyer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Hypoxia induces a novel signature of chromatin modifications and global repression of transcription
Amber Buescher Johnson et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2008)
Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process
Raymond Pfau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cellular oxygen sensing in health and disease
David R. Mole et al.
PEDIATRIC NEPHROLOGY (2008)
Mutations in JARID1C are associated with X-linked mental retardation, short stature and hyperreflexia
F. E. Abidi et al.
JOURNAL OF MEDICAL GENETICS (2008)
JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes
David Frescas et al.
NATURE (2007)
Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis
Yuki Okada et al.
NATURE (2007)
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
Karl Agger et al.
NATURE (2007)
A histone H3 lysine 27 demethylase regulates animal posterior development
Fei Lan et al.
NATURE (2007)
Functional analysis of the transcription repressor PLU-1/JARID1B
Angelo G. Scibetta et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
Francesca De Santa et al.
CELL (2007)
Gene regulation under low oxygen: holding your breath for transcription
Sonia Rocha
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase
Jean-Francois Couture et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
The Drosophila homolog of the putative phosphatidylserine receptor functions to inhibit apoptosis
Ronald J. Krieser et al.
DEVELOPMENT (2007)
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation
Mamta Tahiliani et al.
NATURE (2007)
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases
Shigeki Iwase et al.
CELL (2007)
PLU-1 is an H3K4 dernethylase involved in transcriptional repression and breast cancer cell proliferation
Kenichi Yamane et al.
MOLECULAR CELL (2007)
The retinoblastoma binding protein RBP2 is an H3K4 demethylase
Robert J. Klose et al.
CELL (2007)
Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression
Melanie Wissmann et al.
NATURE CELL BIOLOGY (2007)
Dynamic regulation of histone lysine methylation by demethylases
Yang Shi et al.
MOLECULAR CELL (2007)
Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets
Micah D. Gearhart et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice
Takeshi Suzuki et al.
EMBO JOURNAL (2006)
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
Paul A. C. Cloos et al.
NATURE (2006)
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases
Johnathan R. Whetstine et al.
CELL (2006)
A novel mutation in JARID1C gene associated with mental retardation
C Santos et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2006)
Novel JARID1C/SMCX Mutations in Patients With Xlinked Mental Retardation
A Tzschach et al.
HUMAN MUTATION (2006)
Structural studies on 2-oxoglutarate oxygenases and related double-stranded β-helix fold proteins
Ian J. Clifton et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2006)
Comprehensive genomic analysis of desmoplastic medulloblastomas:: identification of novel amplified genes and separate evaluation of the different histological components
A Ehrbrecht et al.
JOURNAL OF PATHOLOGY (2006)
Histone demethylation by a family of JmjC domain-containing proteins
Y Tsukada et al.
NATURE (2006)
JmjC-domain-containing proteins and histone demethylation
Robert J. Klose et al.
NATURE REVIEWS GENETICS (2006)
Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate
F Laumonnier et al.
JOURNAL OF MEDICAL GENETICS (2005)
Methylation: lost in hydroxylation?
SC Trewick et al.
EMBO REPORTS (2005)
Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation
LR Jensen et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases
P Koivunen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish
JR Hong et al.
DEVELOPMENT (2004)
Phosphatidylserine receptor is required for clearance of apoptotic cells
MO Li et al.
SCIENCE (2003)
Cell corpse engulfment mediated by C-elegans phosphatidylserine receptor through CED-5 and CED-12
XC Wang et al.
SCIENCE (2003)
Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1α
JM Elkins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: A new cancer/testis antigen?
A Barrett et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
D Lando et al.
GENES & DEVELOPMENT (2002)
HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation
F Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)