Smooth muscle cell depletion and collagen types in progeric arteries

Review of two autopsy cases of progeria confirms severe smooth muscle cell (SMC) depletion in the atherosclerotic aortic media and the presence of collagen types I, III, IV, V, and VI in the aorta and renal vessels as is consistent with atherosclerotic disease. (C) 2001 Elsevier Science Inc. All rights reserved.