相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine
Liu Xue et al.
BIOCHEMICAL JOURNAL (2013)
Magnetic Fe3O4@TiO2 nanoparticles-based test strip immunosensing device for rapid detection of phosphorylated butyrylcholinesterase
Xiaoxiao Ge et al.
BIOSENSORS & BIOELECTRONICS (2013)
Gene Transfer of Mutant Mouse Cholinesterase Provides High Lifetime Expression and Reduced Cocaine Responses with No Evident Toxicity
Liyi Geng et al.
PLOS ONE (2013)
Cocaine Hydrolase Encoded in Viral Vector Blocks the Reinstatement of Cocaine Seeking in Rats for 6 Months
Justin J. Anker et al.
BIOLOGICAL PSYCHIATRY (2012)
Are pharmacokinetic approaches feasible for treatment of cocaine addiction and overdose?
Fang Zheng et al.
FUTURE MEDICINAL CHEMISTRY (2012)
Modeling of Pharmacokinetics of Cocaine in Human Reveals the Feasibility for Development of Enzyme Therapies for Drugs of Abuse
Fang Zheng et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
Active Site Gating and Substrate Specificity of Butyrylcholinesterase and Acetylcholinesterase: Insights from Molecular Dynamics Simulations
Lei Fang et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2011)
Design, Preparation, and Characterization of High-Activity Mutants of Human Butyrylcholinesterase Specific for Detoxification of Cocaine
Liu Xue et al.
MOLECULAR PHARMACOLOGY (2011)
Design of High-Activity Mutants of Human Butyrylcholinesterase against (-)-Cocaine: Structural and Energetic Factors Affecting the Catalytic Efficiency
Fang Zheng et al.
BIOCHEMISTRY (2010)
Free-Energy Perturbation Simulation on Transition States and Redesign of Butyrylcholinesterase
Wenchao Yang et al.
BIOPHYSICAL JOURNAL (2009)
Modeling the catalysis of anti-cocaine catalytic antibody: Competing reaction pathways and free energy barriers
Yongmei Pan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Most efficient cocaine hydrolase designed by virtual screening of transition states
Fang Zheng et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats
Stephen Brimijoin et al.
NEUROPSYCHOPHARMACOLOGY (2008)
Pharmacokinetic approaches to treatment of drug addiction
David A Gorelick
Expert Review of Clinical Pharmacology (2008)
New treatments for cocaine dependence:: a focused review
Laurent Karila et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2008)
Free energy perturbation (FEP) simulation on the transition states of cocaine hydrolysis catalyzed by human butyrylcholinesterase and its mutants
Yongmei Pan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Computational redesign of human butyrylcholinesterase for anticocaine medication
YM Pan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
First-principle studies of intermolecular and intramolecular catalysis of protonated cocaine
CG Zhan et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
Molecular dynamics simulation of cocaine binding with human butyrylcholinesterase and its mutants
A Hamza et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2005)
A model of cytokine shedding induced by low doses of gamma radiation
JH Miller et al.
RADIATION RESEARCH (2005)
Large-scale simulations of cellular signaling processes
JH Miller et al.
PARALLEL COMPUTING (2004)
Treating cocaine addiction with viruses
MRA Carrera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cytochrome P450 3A expression and activity in the human small intestine
JS Yang et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products
Y Nicolet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Fundamental reaction mechanism for cocaine hydrolysis in human butyrylcholinesterase
CG Zhan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Neurobiology of butyrylcholinesterase
S Darvesh et al.
NATURE REVIEWS NEUROSCIENCE (2003)
Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase
H Sun et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Re-engineering butyrylcholinesterase as a cocaine hydrolase
H Sun et al.
MOLECULAR PHARMACOLOGY (2002)
Cocaine metabolism in human fetal and adult liver microsomes is related to cytochrome P450 3A expression
MG Ladona et al.
LIFE SCIENCES (2000)
Kinetic characteristics of norcocaine N-hydroxylation in mouse and human liver microsomes:: involvement of CYP enzymes
P Pellinen et al.
ARCHIVES OF TOXICOLOGY (2000)
Determination of the DNA sequences of acetylcholinesterase and butyrylcholinesterase from cat and demonstration of the existence of both in cat plasma
CF Bartels et al.
BIOCHEMICAL PHARMACOLOGY (2000)