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CELL (2006)
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
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NATURE (2006)
Loss of autophagy in the central nervous system causes neurodegeneration in mice
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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
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NATURE GENETICS (2006)
Genotoxicity of chloroquine in rat liver cells: Protective role of free radical scavengers
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CELL BIOLOGY AND TOXICOLOGY (2006)
Inositol and IP3 levels regulate autophagy - Biology and therapeutic speculations
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AUTOPHAGY (2006)
Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells
I Hanukoglu
DRUG METABOLISM REVIEWS (2006)
Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes
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AUTOPHAGY (2006)
The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway (Publication with Expression of Concern. See vol. 295, pg. 8877, 2020) (Withdrawn Publication. See vol. 296, 2021) (Withdrawn Publication. See vol. 296, 2021)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease)
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AMERICAN JOURNAL OF PATHOLOGY (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
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JOURNAL OF CELL BIOLOGY (2005)
The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability
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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
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JOURNAL OF CELL BIOLOGY (2005)
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Caspase-dependent and -independent neuronal death: Two distinct pathways to neuronal injury
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BIOFACTORS (2005)
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
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HUMAN MOLECULAR GENETICS (2005)
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
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SCIENCE (2004)
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products
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BIOCHEMICAL JOURNAL (2004)
Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies
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Role for Rab7 in maturation of late autophagic vacuoles
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WIPI-1α (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy
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ONCOGENE (2004)
NF-κB activation prevents apoptotic oxidative stress via an increase of both thioredoxin and MnSOD levels in TNFα-treated Ewing sarcoma cells
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FEBS LETTERS (2004)
Nitrosative stress linked to sporadic Parkinson's disease:: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
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INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Reactive oxygen species mediate chloroquine-induced expression of chemokines by human astroglial cells
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GLIA (2004)
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LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
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JOURNAL OF CELL SCIENCE (2004)
Rab7 is required for the normal progression of the autophagic pathway in mammalian cells
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Activation of p53 by oxidative stress involves platelet-derived growth factor-β receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The role of pathogenic DJ-1 mutations in Parkinson's disease
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
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FEBS LETTERS (2003)
Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer's and Parkinson's diseases
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NEUROMOLECULAR MEDICINE (2003)
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Loss of cardiolipin and mitochondria during programmed neuronal death: Evidence of a role for lipid peroxidation and autophagy
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Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells
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