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CELL (2006)
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
Diane Crighton et al.
CELL (2006)
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara et al.
NATURE (2006)
Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu et al.
NATURE (2006)
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
A Bender et al.
NATURE GENETICS (2006)
Genotoxicity of chloroquine in rat liver cells: Protective role of free radical scavengers
EO Farombi
CELL BIOLOGY AND TOXICOLOGY (2006)
Inositol and IP3 levels regulate autophagy - Biology and therapeutic speculations
Sovan Sarkar et al.
AUTOPHAGY (2006)
Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells
I Hanukoglu
DRUG METABOLISM REVIEWS (2006)
Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes
Sara Rodriguez-Enriquez et al.
AUTOPHAGY (2006)
The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway (Publication with Expression of Concern. See vol. 295, pg. 8877, 2020) (Withdrawn Publication. See vol. 296, 2021) (Withdrawn Publication. See vol. 296, 2021)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease)
M Koike et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
G Bjorkoy et al.
JOURNAL OF CELL BIOLOGY (2005)
The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability
SA Dames et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
M Komatsu et al.
JOURNAL OF CELL BIOLOGY (2005)
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Caspase-dependent and -independent neuronal death: Two distinct pathways to neuronal injury
L Stefanis
NEUROSCIENTIST (2005)
Inhibition of defective adenylosuccinate lyase by HNE: A neurological disease that may be affected by oxidative stress
C Crifo et al.
BIOFACTORS (2005)
Inhibition of ion transport ATPases by HNE
C Crifo et al.
BIOFACTORS (2005)
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
DJ Moore et al.
HUMAN MOLECULAR GENETICS (2005)
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
AV Budanov et al.
SCIENCE (2004)
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products
AL Levonen et al.
BIOCHEMICAL JOURNAL (2004)
Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies
PA Trimmer et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Role for Rab7 in maturation of late autophagic vacuoles
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JOURNAL OF CELL SCIENCE (2004)
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
A Simonsen et al.
JOURNAL OF CELL SCIENCE (2004)
WIPI-1α (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy
T Proikas-Cezanne et al.
ONCOGENE (2004)
NF-κB activation prevents apoptotic oxidative stress via an increase of both thioredoxin and MnSOD levels in TNFα-treated Ewing sarcoma cells
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FEBS LETTERS (2004)
Nitrosative stress linked to sporadic Parkinson's disease:: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity
DD Yao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
LC3 conjugation system in mammalian autophagy
I Tanida et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Reactive oxygen species mediate chloroquine-induced expression of chemokines by human astroglial cells
JS Park et al.
GLIA (2004)
High frequency of mitochondrial complex I mutations in Parkinson's disease and aging
R Smigrodzki et al.
NEUROBIOLOGY OF AGING (2004)
Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease
DK Simon et al.
NEUROBIOLOGY OF AGING (2004)
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
Y Kabeya et al.
JOURNAL OF CELL SCIENCE (2004)
Rab7 is required for the normal progression of the autophagic pathway in mammalian cells
MG Gutierrez et al.
JOURNAL OF CELL SCIENCE (2004)
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
EM Valente et al.
SCIENCE (2004)
Activation of p53 by oxidative stress involves platelet-derived growth factor-β receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation
K Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The role of pathogenic DJ-1 mutations in Parkinson's disease
PM Abou-Sleiman et al.
ANNALS OF NEUROLOGY (2003)
Selective degradation of oxidatively modified protein substrates by the proteasome
T Grune et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Redox catalysts as sensitisers towards oxidative stress
NM Giles et al.
FEBS LETTERS (2003)
Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer's and Parkinson's diseases
M Hashimoto et al.
NEUROMOLECULAR MEDICINE (2003)
Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species
CE Cooper et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
Cellular response to oxidative stress: Signaling for suicide and survival
JL Martindale et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2002)
Tyrosine 125 of α-synuclein plays a critical role for dimerization following nitrative stress
T Takahashi et al.
BRAIN RESEARCH (2002)
Mitochondrial dysfunction in the neuronal ceroid-lipofuscinoses (Batten disease)
RD Jolly et al.
NEUROCHEMISTRY INTERNATIONAL (2002)
Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans
RJ Castellani et al.
NEUROSCIENCE LETTERS (2002)
Loss of cardiolipin and mitochondria during programmed neuronal death: Evidence of a role for lipid peroxidation and autophagy
RA Kirkland et al.
NEUROSCIENCE (2002)
Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells
R Shringarpure et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2001)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)
I Nishino et al.
NATURE (2000)
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice
Y Tanaka et al.
NATURE (2000)
Dityrosine cross-linking promotes formation of stable α-synuclein polymers -: Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies
JM Souza et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells
SW Ballinger et al.
CIRCULATION RESEARCH (2000)