相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Identification of Heterogeneous Nuclear Ribonucleoprotein K as a Transactivator for Human Low Density Lipoprotein Receptor Gene Transcription
Hai Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Functional analysis of rat liver citrate carrier promoter: differential responsiveness to polyunsaturated fatty acids
Fabrizio Damiano et al.
BIOCHEMICAL JOURNAL (2009)
PCSK9 as a therapeutic target of dyslipidemia
Nabil G. Seidah
EXPERT OPINION ON THERAPEUTIC TARGETS (2009)
Hepatocyte Nuclear Factor 1α Plays a Critical Role in PCSK9 Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine
Hai Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
PCSK9: a convertase that coordinates LDL catabolism
Jay D. Horton et al.
JOURNAL OF LIPID RESEARCH (2009)
Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements
Hai Li et al.
JOURNAL OF LIPID RESEARCH (2009)
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates
Joyce C. Y. Chan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Berberine decreases PCSK9 expression in HepG2 cells
Jamie Cameron et al.
ATHEROSCLEROSIS (2008)
Inhibition of PCSK9 as a Novel Strategy for the Treatment of Hypercholesterolemia
Dayami Lopez
DRUG NEWS & PERSPECTIVES (2008)
Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor
Da-Wei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
Maria Frank-Kamenetsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
PCSK9 and LDL cholesterol: unravelling the target to design the bullet
Philippe Costet et al.
TRENDS IN BIOCHEMICAL SCIENCES (2008)
Sterol-dependent regulation of proprotein convertase subtilisin/kexin type 9 expression by sterol-regulatory element binding protein-2
Hyun Jeong Jeong et al.
JOURNAL OF LIPID RESEARCH (2008)
Transcriptional activation of histone genes requires NPAT-Dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G(1)/S phase transition
Michael DeRan et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
The HINF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes
Ricardo Medina et al.
CANCER RESEARCH (2007)
Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis
Yue-Wei Qian et al.
JOURNAL OF LIPID RESEARCH (2007)
Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat a of low density lipoprotein receptor decreases receptor recycling and increases degradation
Da-Wei Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice
Mark J. Graham et al.
JOURNAL OF LIPID RESEARCH (2007)
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice
Thomas A. Lagace et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
JC Cohen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Protocol for the fast chromatin immunoprecipitation (ChIP) method
Joel D. Nelson et al.
NATURE PROTOCOLS (2006)
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
R Murr et al.
NATURE CELL BIOLOGY (2006)
Severe hypercholesterolemia in four British families with the D374Y mutation in the PCSK9 gene - Long-term follow-up and treatment response
RP Naoumova et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition
A Miele et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9
C Jonathan et al.
NATURE GENETICS (2005)
Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia
TP Leren
CLINICAL GENETICS (2004)
A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree
KM Timms et al.
HUMAN GENETICS (2004)
Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia
G Dubuc et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression
H Li et al.
EMBO JOURNAL (2004)
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
WJ Kong et al.
NATURE MEDICINE (2004)
Sequence-specific transcriptional repression by an MBD2-interacting zinc finger protein MIZF
M Sekimata et al.
NUCLEIC ACIDS RESEARCH (2004)
SREBP transcription factors:: master regulators of lipid homeostasis
D Eberlé et al.
BIOCHIMIE (2004)
Genome-wide analysis of gene expression regulated by the HAT cofactor Trrap in conditional knockout cells
Z Herceg et al.
NUCLEIC ACIDS RESEARCH (2003)
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
JD Horton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
MYC recruits the TIP60 histone acetyltransferase complex to chromatin
SR Frank et al.
EMBO REPORTS (2003)
The diverse functions of histone acetyltransferase complexes
MJ Carrozza et al.
TRENDS IN GENETICS (2003)
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
M Abifadel et al.
NATURE GENETICS (2003)
Histone acetylation and deacetylation in yeast
SK Kurdistani et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2
M Sekimata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation of cyclin D2 gene expression by the Myc/Max/Mad network:: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter
C Bouchard et al.
GENES & DEVELOPMENT (2001)
Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation
SR Frank et al.
GENES & DEVELOPMENT (2001)
The many HATs of transcription coactivators
CE Brown et al.
TRENDS IN BIOCHEMICAL SCIENCES (2000)
分享论文
