4.5 Review

Mechanisms and functions of p38 MAPK signalling

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Nuclear Localization of p38 MAPK in Response to DNA Damage

C. David Wood et al.

International Journal of Biological Sciences (2012)

Article Cell Biology

Differential activation of p38MAPK isoforms by MKK6 and MKK3

Gaelle Remy et al.

CELLULAR SIGNALLING (2010)

Article Biochemistry & Molecular Biology

Coordinated regulation of autophagy by p38α MAPK through mAtg9 and p38IP

Jemma L. Webber et al.

EMBO JOURNAL (2010)

Review Biochemistry & Molecular Biology

Multilayered control of gene expression by stress-activated protein kinases

Eulalia de Nadal et al.

EMBO JOURNAL (2010)

Review Biochemistry & Molecular Biology

WIP1 phosphatase at the crossroads of cancer and aging

Xavier Le Guezennec et al.

TRENDS IN BIOCHEMICAL SCIENCES (2010)

Article Biochemical Research Methods

The three-dimensional structure of MAP kinase p38β: different features of the ATP-binding site in p38β compared with p38α

Sangita B. Patel et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

p38α Is Active in Vitro and in Vivo When Monophosphorylated at Threonine 180

Nadav Askari et al.

BIOCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis

Grzegorz Sumara et al.

Review Pharmacology & Pharmacy

Peptides as Signaling Inhibitors for Mammalian MAP Kinase Cascades

Matthias Gaestel et al.

CURRENT PHARMACEUTICAL DESIGN (2009)

Article Biochemistry & Molecular Biology

Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression

Arne Lindqvist et al.

EMBO JOURNAL (2009)

Article Biochemistry & Molecular Biology

Selectivity of Docking Sites in MAPK Kinases

A. Jane Bardwell et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

MKK4/SEK1 Is Negatively Regulated through a Feedback Loop Involving the E3 Ubiquitin Ligase Itch

Young-Ho Ahn et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Target Gene Specificity of USF-1 Is Directed via p38-mediated Phosphorylation-dependent Acetylation

Sebastien Corre et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Cell Biology

p38-γ-dependent gene silencing restricts entry into the myogenic differentiation program

Mark A. Gillespie et al.

JOURNAL OF CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

p38α MAP Kinase C-Terminal Domain Binding Pocket Characterized by Crystallographic and Computational Analyses

J. Jefferson P. Perry et al.

JOURNAL OF MOLECULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

p38 Mitogen-Activated Protein Kinase- and HuR-Dependent Stabilization of p21Cip1 mRNA Mediates the G1/S Checkpoint

Vanesa Lafarga et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Cell Biology

WIP1 phosphatase is a negative regulator of NF-κB signalling

Joanne Chew et al.

NATURE CELL BIOLOGY (2009)

Article Biochemical Research Methods

RNF2 is the target for phosphorylation by the p38 MAPK and ERK signaling pathways

Prema S. Rao et al.

PROTEOMICS (2009)

Article Biochemistry & Molecular Biology

Increased MKK4 Abundance with Replicative Senescence Is Linked to the Joint Reduction of Multiple MicroRNAs

Bernard S. Marasa et al.

SCIENCE SIGNALING (2009)

Article Biochemistry & Molecular Biology

MSK2 Inhibits p53 Activity in the Absence of Stress

Susana Llanos et al.

SCIENCE SIGNALING (2009)

Article Cell & Tissue Engineering

p38 MAP Kinase Inhibits Neutrophil Development Through Phosphorylation of C/EBP alpha on Serine 21

Christian R. Geest et al.

STEM CELLS (2009)

Article Biochemistry & Molecular Biology

The Structure of the MAP2K MEK6 Reveals an Autoinhibitory Dimer

Xiaoshan Min et al.

STRUCTURE (2009)

Review Biochemistry & Molecular Biology

p38MAPK: stress responses from molecular mechanisms to therapeutics

Lydia R. Coulthard et al.

TRENDS IN MOLECULAR MEDICINE (2009)

Review Oncology

Signal integration by JNK and p38 MAPK pathways in cancer development

Erwin F. Wagner et al.

NATURE REVIEWS CANCER (2009)

Article Biochemistry & Molecular Biology

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

Yan Zeng et al.

BIOCHEMICAL JOURNAL (2008)

Review Biochemistry & Molecular Biology

Phosphatase-mediated crosstalk between MAPK signalling pathways in the regulation of cell survival

Melissa R. Junttila et al.

FASEB JOURNAL (2008)

Article Biochemistry & Molecular Biology

Enzymatic activity and substrate specificity of mitogen-activated protein kinase p38α in different phosphorylation states

Yuan-Yuan Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

AMP-activated protein kinase and p38 MAPK activate O-GlcNAcylation of neuronal proteins during glucose deprivation

Win D. Cheung et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

ATR-dependent activation of p38 MAP kinase is responsible for apoptotic cell death in cells depleted of Cdc7

Jun-Sub Im et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-β

Motozo Yamashita et al.

MOLECULAR CELL (2008)

Article Cell Biology

The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Alessandro Sorrentino et al.

NATURE CELL BIOLOGY (2008)

Article Multidisciplinary Sciences

Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex

Atsushi Matsuzawa et al.

SCIENCE (2008)

Article Multidisciplinary Sciences

Phosphorylation by p38 MAPK as an alternative pathway for GSK3β inactivation

Tina M. Thornton et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase

Yongqun Zhu et al.

MOLECULAR CELL (2007)

Article Biochemistry & Molecular Biology

p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation

Shravanti Rampalli et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3β

Amy N. Abell et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

The chromatin remodeling protein, SRCAP, is critical for deposition of the histone variant H2A.Z at promoters

Madeline M. Wong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Biochemistry & Molecular Biology

P38 MAP-Kinases pathway regulation, function and role in human diseases

Ana Cuenda et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)

Article Biochemistry & Molecular Biology

Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex

Rui Wu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

High-resolution profiling of histone methylations in the human genome

Artern Barski et al.

Review Biochemistry & Molecular Biology

Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases

D. M. Owens et al.

ONCOGENE (2007)

Review Biochemistry & Molecular Biology

Role of mitogen-activated protein kinase kinase kinases in signal integration

B. D. Cuevas et al.

ONCOGENE (2007)

Article Biochemistry & Molecular Biology

A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis

Ana Cuadrado et al.

EMBO JOURNAL (2007)

Article Multidisciplinary Sciences

Molecular basis of MAPK-activated protein kinase 2:p38 assembly

Andre White et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

Crystal structure of the P38α-MAPKAP kinase 2 heterodimer

Ernst ter Haar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Mxi2 promotes stimulus-independent ERK nuclear translocation

Berta Casar et al.

EMBO JOURNAL (2007)

Review Pharmacology & Pharmacy

Novel strategies for inhibition of the p38 MAPK pathway

Jiyan Zhang et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2007)

Article Biochemistry & Molecular Biology

Regulation of the ring finger E3 ligase Siah2 by p38 MAPK

Ashwani Khurana et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK

Sandra Peregrin et al.

CURRENT BIOLOGY (2006)

Article Biochemistry & Molecular Biology

p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy

Yaara Zwang et al.

EMBO JOURNAL (2006)

Article Multidisciplinary Sciences

Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation

Sohini Mukherjee et al.

SCIENCE (2006)

Article Biochemistry & Molecular Biology

Determinants that control the specific interactions between TAB1 and p38α

Huamin Zhou et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

TAB-1 modulates intracellular localization of p38 MAP kinase and downstream signaling

L Gang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Review Cell Biology

Regulation of skeletal muscle gene expression by p38 MAP kinases

F Lluis et al.

TRENDS IN CELL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Generation and characterization of p38β (MAPK11) gene-targeted mice

VA Beardmore et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Biochemistry & Molecular Biology

p38 mitogen-activated protein kinase plays a key role in regulating MAPKAPK2 expression

T Sudo et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Article Biochemistry & Molecular Biology

Phosphorylation of EEA1 by p38 MAP kinase regulates μ opioid receptor endocytosis

T Macé et al.

EMBO JOURNAL (2005)

Article Biochemistry & Molecular Biology

Essential role of p38γ in K-ras transformation independent of phosphorylation

J Tang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways

N Kelkar et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Biotechnology & Applied Microbiology

A small molecule-kinase interaction map for clinical kinase inhibitors

MA Fabian et al.

NATURE BIOTECHNOLOGY (2005)

Article Biochemistry & Molecular Biology

Discovery and characterization of a substrate selective p38α inhibitor

W Davidson et al.

BIOCHEMISTRY (2004)

Review Biochemistry & Molecular Biology

The ASK1-MAP kinase cascades in mammalian stress response

J Matsukawa et al.

JOURNAL OF BIOCHEMISTRY (2004)

Review Microbiology

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

PP Roux et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2004)

Article Multidisciplinary Sciences

An efficient proteomics method to identify the cellular targets of protein kinase inhibitors

K Godl et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Feedback control of the protein kinase TAK1 by SAPK2a/p38α

PCF Cheung et al.

EMBO JOURNAL (2003)

Review Biotechnology & Applied Microbiology

p38 map kinases: Key signalling molecules as therapeutic targets for inflammatory diseases

S Kumar et al.

NATURE REVIEWS DRUG DISCOVERY (2003)

Article Cell Biology

Mechanism of p38 MAP kinase activation in vivo

D Brancho et al.

GENES & DEVELOPMENT (2003)

Article Biochemistry & Molecular Biology

ERK1/2 achieves sustained activation by stimulating MAPK phosphatase-1 degradation via the ubiquitin-proteasome pathway

YW Lin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14

A Soloaga et al.

EMBO JOURNAL (2003)

Article Biochemistry & Molecular Biology

Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II

PM Alepuz et al.

EMBO JOURNAL (2003)

Review Biochemistry & Molecular Biology

Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions

RM Biondi et al.

BIOCHEMICAL JOURNAL (2003)

Article Biochemistry & Molecular Biology

Anthrax lethal factor proteolysis and inactivation of MAPK kinase

AP Chopra et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Letter Cell Biology

Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock

MT Uhlik et al.

NATURE CELL BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Negative feedback regulation of MKK6 mRNA stability by p38 alpha mitogen-activated protein kinase

C Ambrosino et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Review Cell Biology

Regulation of map kinase signaling modules by scaffold proteins in mammals

DK Morrison et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2003)

Review Biochemistry & Molecular Biology

In the cellular garden of forking paths: How p38 MAPKs signal for downstream assistance

Y Shi et al.

BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

C Pargellis et al.

NATURE STRUCTURAL BIOLOGY (2002)

Review Cell Biology

Regulation of MAP kinases by docking domains

H Enslen et al.

BIOLOGY OF THE CELL (2001)

Article Biochemistry & Molecular Biology

The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex

V Cavalli et al.

MOLECULAR CELL (2001)

Article Biochemistry & Molecular Biology

Differential activation of p38 mitogen-activated protein kinase isoforms depending on signal strength

G Alonso et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Multidisciplinary Sciences

Essential role for p38α mitogen-activated protein kinase in placental angiogenesis

JS Mudgett et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Biochemistry & Molecular Biology

Essential role of p38α MAP kinase in placental but not embryonic cardiovascular development

RH Adams et al.

MOLECULAR CELL (2000)

Article Biochemistry & Molecular Biology

p38 MAP kinases: beyond the stress response

AR Nebreda et al.

TRENDS IN BIOCHEMICAL SCIENCES (2000)

Review Cell Biology

The p38 signal transduction pathway - Activation and function

K Ono et al.

CELLULAR SIGNALLING (2000)