期刊
BIOCHEMICAL JOURNAL
卷 426, 期 -, 页码 1-11出版社
PORTLAND PRESS LTD
DOI: 10.1042/BJ20091571
关键词
host cell shut-off; poly(A)-binding protein (PABP); RNA-binding protein; translational activation and/or repression; translation initiation; virus
资金
- Medical Research Council Senior Non-Clinical Research
- Medical Research Council [U1276.00.002.00011.011]
- Wellcome Trust
- Medical Research Council [G117/564, G9826324] Funding Source: researchfish
- MRC [G9826324, G117/564] Funding Source: UKRI
Cytoplasmic PABP [poly(A)-binding protein] is a multifunctional protein with well-studied roles ill mRNA translation and stability. Ill the present review, we examine recent evidence that the activity of PABP is altered during infection with it wide range of viruses, bringing about changes ill its stability, complex formation and intracellular localization. Targeting of PABP by both RNA and DNA viruses highlights the role of PABP as a central regulator of gene expression.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据