期刊
JOURNAL OF BIOLOGICAL CHEMISTRY
卷 290, 期 31, 页码 18984-18990出版社
AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
DOI: 10.1074/jbc.R115.643973
关键词
-
资金
- National Institutes of Health [R01ES0146380, R01DK064570]
During the course of infection, many natural defenses are set up along the boundaries of the host-pathogen interface. Key among these is the host response to withhold metals to restrict the growth of invading microbes. This simple act of nutritional warfare, starving the invader of an essential element, is an effective means of limiting infection. The physiology of metal withholding is often referred to as nutritional immunity, and the mechanisms of metal transport that contribute to this host response are the focus of this review.
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