期刊
GENE
卷 269, 期 1-2, 页码 45-51出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0378-1119(01)00454-1
关键词
New World monkeys; color vision; fluorescence in situ hybridization (FISH); X chromosome; in vitro regeneration
资金
- NIGMS NIH HHS [GM42379] Funding Source: Medline
The genetic basis of red-green color vision of common marmoset (Callithrix jacchus) is not fully understood. Here, we have cloned and characterized the three alleles at a locus that encode the long to middle wavelength-sensitive (LWS/MWS) visual pigments of this species. Using in Situ hybridization, we localized this locus to the telomeric region of the long arm of X chromosome. The three visual pigments achieve the wavelengths of maximal absorption at 561, 553, and 539 nm and fully explain the red-green color vision of the common marmoset. The 'tri-allelic single-locus X-chromosome' model operates under the unique phenomenon, known as blood chimerism. (C) 2001 Elsevier Science B.V. All rights reserved.
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