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In situ oxidation-imine formation-reduction routes from alcohols to amines

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卷 3, 期 11, 页码 1637-1639

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AMER CHEMICAL SOC
DOI: 10.1021/ol015819b

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[GRAPHICS] Manganese dioxide is employed as an in situ oxidant for the one pot conversion of alcohols into imines, In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence is reported, This procedure enables alcohols to be converted directly into both secondary and tertiary amines.

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